This dataset provides estimates of vaccination coverage for meningococcal serogroup A conjugate vaccine (MenAfriVac®) for 24 countries in the meningitis belt of sub-Saharan Africa between 2010 and 2021. Indicators include mean and 95% uncertainty intervals for the estimated coverage for children aged 1 to 5 and children and young adults aged 1 to 29. These estimates include coverage from both mass vaccination campaigns and routine immunization delivery. The estimation process primarily utilized survey report data and country-reported administrative vaccine coverage data.